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Stationary Phases for the Process Scale Purification of Peptides and Insulin Analogs (TN-1233)
In this technical note the analog Insulin Glargine was used to demonstrate the comparability of the high pH resistant silica to that of a typical silica used in industry chromatographically. Multiple fractions were assayed from both Luna C8(3) and high pH stable Gemini C8(3). These two media were found to be comparable and yield insulin glargine at greater than 98% purity.
Stationary Phases for the Process Scale Purification of Peptides and Insulin Analogs (TN-1233)
In this technical note the analog Insulin Glargine was used to demonstrate the comparability of the high pH resistant silica to that of a typical silica used in industry chromatographically. Multiple fractions were assayed from both Luna C8(3) and high pH stable Gemini C8(3). These two media were found to be comparable and yield insulin glargine at greater than 98% purity.