Novum Simplified Liquid Extraction

Simplify Your Liquid-Liquid Extractions with Faster, Easier, and More Reliable SLE

Novum Simplified Liquid Extraction (SLE) (patent pending) products are a faster, easier, and more reliable way to perform liquid-liquid extractions. In 3 easy steps and less than 15 minutes, you can remove unwanted interferences such as salts, proteins, phospholipids and more from a variety of samples without performing extensive method development.

New Novum PRO SLE to get down to low (LLOD) extraction levels from plasma

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A Simplified Liquid Extraction

Novum SLE will instantly increase your throughput by eliminating time consuming steps and reducing the risk of analyte loss. If further time savings are necessary, Novum SLE can be easily automated for rapid, hands free sample cleanup.

Slow and Laborious

Traditional
Liquid-Liquid Extraction¹

Estimated Time per Sample = 25 minutes

1.	Dilute sample 1:1 with buffer or water and add extraction solvent
2.	Mix for 10 minutes
3.	Centrifuge for 10 minutes
4.	Pour off or freeze supernatant

Fast and Easy

Novum Simplified
Liquid Extraction (SLE)

Estimated Time per Sample = < 15 minutes

1.	Dilute sample 1:1 with buffer or water and load onto Novum SLE sorbent using 2–15 seconds of vacuum
2.	Wait 5 minutes
3.	Apply elution solvent and allow to elute via gravity. Complete elution with 10 seconds of vacuum.
	Rapid, automatable method for high-throughput cleanup Stop worrying about analyte loss due to emulsions

1. Russell Grant, Matthew Crawford, Brian Rappold, and Stacy Dee. Errors in Bioanalysis Due to Phospholipids – Definitive Measurement, Mechanism, and Management. ASMS 2011.

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