Preventing Analyte Loss by Skipping the Dry Down Step using Microelution Solid Phase Extraction (SPE) (TN-0086)

Sample preparation can often pose a challenge when working with thermolabile or very hydrophobic compounds because these analytes are susceptible to analyte loss, particularly during a dry down step. This technical note describes an ultra-sensitive sample preparation technique using microelution 96-well SPE plates that allows analysts to eliminate a dry down step, thus increasing their recoveries.