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Low Concentration Amphetamines by SPE and LC-MS/MS (TN-0020)
Use of Strata-X-C SPE cartridges allows for an aggressive organic wash of biological samples while maintaining high recoveries of amphetamines and their metabolites. In combination with LC-MS/MS, limits of quantitation (LOQ) of 0.54 ng/mL are achieved for MAMPH, HMMA, and MDMA and LOQ of 1.0 ng/mL are achieved for AMPH and MDA on Gemini C18 HPLC columns
Low Concentration Amphetamines by SPE and LC-MS/MS (TN-0020)
Use of Strata-X-C SPE cartridges allows for an aggressive organic wash of biological samples while maintaining high recoveries of amphetamines and their metabolites. In combination with LC-MS/MS, limits of quantitation (LOQ) of 0.54 ng/mL are achieved for MAMPH, HMMA, and MDMA and LOQ of 1.0 ng/mL are achieved for AMPH and MDA on Gemini C18 HPLC columns