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Aggregate Analysis of Monoclonal Antibodies using Biozen SEC-3 Column
Monoclonal antibody (mAb) aggregates have significant implications in safety, immunogenicity, and efficacy for therapeutic drug development. Size exclusion chromatography (SEC) is one of the laboratory methods used to determine the extent of aggregation of a protein. This method demonstrates the separation of three mAbs trastuzumab, infliximab, and cetuximab with the use of the Biozen SEC-3 column.
Aggregate Analysis of Monoclonal Antibodies using Biozen SEC-3 Column
Monoclonal antibody (mAb) aggregates have significant implications in safety, immunogenicity, and efficacy for therapeutic drug development. Size exclusion chromatography (SEC) is one of the laboratory methods used to determine the extent of aggregation of a protein. This method demonstrates the separation of three mAbs trastuzumab, infliximab, and cetuximab with the use of the Biozen SEC-3 column.
Document Type:
Technical Notes
Target Industries:
Brands:
Separation Modes:
Size Exclusion
Phases:
Aggregate Analysis of Monoclonal Antibodies using Biozen SEC-3 Column
Monoclonal antibody (mAb) aggregates have significant implications in safety, immunogenicity, and efficacy for therapeutic drug development. Size exclusion chromatography (SEC) is one of the laboratory methods used to determine the extent of aggregation of a protein. This method demonstrates the separation of three mAbs trastuzumab, infliximab, and cetuximab with the use of the Biozen SEC-3 column.
| Target Industries: | Biopharmaceutical Analysis, Pharmaceutical |
| Techniques: | HPLC, HPLC-SEC |
| Brands: | Biozen LC |
| Separation Modes: | Size Exclusion |
| Phases: | Biozen-SEC-3 |
Phenomenex is a technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers worldwide
Phenomenex is a technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers worldwide