Ion Exclusion (IEC)

Ion exclusion (IEC) chromatography is a process of separating components in a mixture by means of an ion-exchange resin that excludes highly ionized particles and retains slightly ionized or non-ionized particles. Ion exclusion (IEC) chromatography applies to the retention of organic acids, carbohydrates, sugars, starches, and oligosaccharides, using a sulfonated stationary phase.

From drug formulation and excipient analysis to quality control testing of finished food products to fermentation monitoring of bioethanol production, ion exclusion provides the necessary accurate and reproducible analytical results.