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Applications
Bisoprolol on Lux 5µm Cellulose-1 by SFC
21054
Separation Mode: Chiral
Chiral
Cellulose-1
HPLC
Antihypertensive Agents
Pharmaceutical/Biopharmaceutical
Chemical Compound
Therapeutic / Clinical
Therapeutic / Clinical

Applications

Bisoprolol on Lux 5µm Cellulose-1 by SFC
Analytes
1Bisoprolol
2Bisoprolol
Compound Name
Bisoprolol
CID
2405
Molecular Formula
C18H31NO4
Molecular Weight
325
No. Chiral Centers:
1
No. Hydrogen Bond Acceptors
5
No. Hydrogen Bond Donors
2
Details
LC Conditions (App ID: 21054)
Column:
Brand Name:
Part No:
Phase Name:
Cellulose-1
Elution Type:
Isocratic
Mobile Phase:
A: CO2/(Isopropanol + 0.5% IPA) 80:20 (v/v)
Gradient Profile:
Step No.Time(min)%A
10100
Flow Rate:
3 mL/min
Temperature:
30°C
Detection:
UV-Vis Abs.-Diode Array (PDA) @ 220 nm (30°C)
Sample Note:
Courtesy of Katrijn De Klerck, Debby Mangelings and Yvan Vander Heyden, Department of Analytical Chemistry and Pharmaceutical Technology, Vrije Universiteit Brussel, Brussels, Belgium. Results of this analysis yielded: Alpha >1.1 and Resolution >1.5 SecurityGuard™ Guard Cartridge System extends column lifetime. - SecurityGuard Cartridges, Lux Cellulose-1, 4 x 3.0mm ID, 10/Pk Part No.: AJ0-8403 - Holder Part No.: KJ0-4282

Order Items Used in This Application

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