| 1Terfenadine |
|---|
| 2Terfenadine |
Compound Name Terfenadine |
CID 5405 |
Molecular Formula C32H41NO2 |
Molecular Weight 471 |
No. Chiral Centers: 1 |
No. Hydrogen Bond Acceptors 3 |
No. Hydrogen Bond Donors 2 |
Applications
Terfenadine on Lux 5 µm Cellulose-1 by Chiral SFC (loading and scale up)
18867
Separation Mode: Chiral
Chiral
Cellulose-1
HPLC
Pharmaceutical/Biopharmaceutical
Therapeutic / Clinical
Therapeutic / Clinical
Chemical Compound
Analytes
Details
LC Conditions (App ID: 18867)
Column: | ||||||||
Brand Name: | ||||||||
Part No: | ||||||||
Phase Name: Cellulose-1 | ||||||||
Elution Type: Isocratic | ||||||||
Mobile Phase: A: Methanol with 0.1% DEA B: CO2 | ||||||||
Gradient Profile:
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Flow Rate: 50 mL/min | ||||||||
Temperature: 35°C | ||||||||
Detection: UV-Vis Abs.-Diode Array (PDA) @ 220 nm (22°C) | ||||||||
Sample Note: Application using combination of UV-Vis detector red trace) and PDR-Chiral Advanced Laser Polarimeter blue trace) showing 3 purification cycles. Courtesy of PDR-Chiral, Inc.
105mg in 3.5mL on-column injection of Terfenadine. |
Order Items Used in This Application
00G-4459-P0-AX
Lux 5 µm Cellulose-1, LC Column 250 x 21.2 mm, AXIA Packed, Ea
Qty:
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