Available in two flash medias (Irregular and Spherical) with multiple chemistries optimized for resolution and high loading capacity.
Claricep CM utilizes silica that is further purified with a proprietary acid washing process which results in even lower surface activity to result in an improved peak shape and resolution.
Consistent High Performance: High loading capacity (high surface area > 350m2/g) combined with good resolution for tight band definition (no tailing)
Wide Range of Selectivities: Variety of sorbents to meet any separation needs -(Silica (Si), C18, C8, AQ C18, Phenyl, Cyano (CN), Diol (OH), Amino (NH2) and HILIC (Urea) along with a large variety of cartridge sizes from 4 g to several kilograms allows for purification scale-up from milligrams to kilograms
High Pressure Tolerance: Exceptional durability to withstand high pressures due to closed-top spin-welded technology on standard hardware sizes that allows for pressure up to 12 bar (180 PSI)
Excellent Hardware: Universal luer fittings for compatibility with any flash system for great compound purity & recovery and 100% guaranteed leak-free.
High Quality: Consistent homogeneous packing allows for no channeling and creates reproducible high plate count (N).
Dimension
4.6 x 150 mm
|
Mobile Phase
Dichloromethane/Methanol (98:2)
|
Flow Rate
1.8 mL/min |
Injection Volume
5 μL |
Temperature
30 °C |
Detector:
1.8 mL/min |
UV @ 254 nm
1.8 mL/min |
Sample
Catechol 100 μg/mL |
HPLC TEST
Unmodified and Deactivated Silica were packed into individual
stainless steel columns (4.6 x 150 mm) and then evaluated on a
HPLC System |
Ultra pure packing which results in much less abnormal surface activity. This produces chromatograms with much sharper peaks
Column
Claricep Irregular Silica CS (40-60 μm, 60 Å, 40 g)
|
Brand I
Flash Irregular Silica (40 g)
|
Mobile Phase
Dichloromethane/Methanol (99:1)
|
Flow Rate
20 mL/min |
Detector
UV @ 254 nm |
Temperature
Ambient |
Retention Time
CLARICEP CS: 4.090 minBrand I: 4.373 min |
Sample
Aniline |
Column
Claricep Irregular Silica CS
(40-60 μm, 60 Å, 40 g) |
Brand I
Flash Irregular Silica Column (40 g)
|
Mobile Phase
Hexane/Ethylacetate (gradient)
|
Detector
UV @ 254 nm |
Temperature
Ambient |
Retention Time
CLARICEP CS: 4.090 minBrand I: 4.373 min |
Sample
Phenyl acetone,4-aminobenzoic acid |
Regular, similar-sized and high quality particles can be packed in a column much more uniformly which reduces eddy flow currents and lateral diffusion. The result is greater peak symmetry and baselineresolution than is possible with irregular silica particles.
Column A
Claricep Spherical Silica (20-35 μm, 100 Å, 12 g,
2 columns in tandem)
|
|
Column B
Claricep Spherical Silica (20 μm, 100 Å, 12 g,
2 columns in tandem
|
|
Mobile Phase:
A: Hexane B: Ethanol |
|
Gradient:
Time (min)
0
20 | % B
5 55 |
Flow Rate:
12 mL/min |
|
Detector
UV @ 254/220 nm (ambient) |
|
Samples:
0.2 mL |